Keith also offers a complete week weight loss course that therapists can utilize in their practice to implement a ketogenic treatment program for their clients. In the case of lymphedema, it would be weight loss and reduction in lymphedema volume. Fill in with fat for satiation. Primary lymphedema is a rare, congenital disorder caused by inherited genetic mutation on a number of genes that are essential for lymphatic vessel development and function. This fat burning produces ketones. Given the promising findings in the mouse experiments by professor Carmeliet, we are hopeful to see positive effects of a ketogenic diet also in patients”, concludes dr. Ketogenic Diet Resource. Then the interviewer who knew what treatment they selected delivered the program.
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Lymphedema is a debilitating disorder that severely impairs the quality of life of the patients and requires life-long attention. Treatment for lymphatic dysfunction remains largely symptomatic, without real cure. According to the International Society of Lymphology, lymphedema has to be treated with Decongestive Lymphatic Therapy. Research in the lab of Angiogenesis and Vascular Metabolism PCA lab reported in mice that metabolism of endothelial cells controls vessel sprouting. Experiments showed that a ketogenic diet KD reduced the edema of the mice tail and enhanced the lymphatic transport. Based on these proof-of-concept data, the investigators plan to test this innovative concept to ameliorate lymph vessel dysfunction in lymphedema patients. Randomisation will be performed between a ketogenic diet and a isocaloric diet.
At the cellular level, perturbed or dysfunctional lymphatic drainage triggers accumulation of interstitial fluid, negatively affects cellular behavior, and induces infiltration of fibroblasts, adipocytes and keratinocytes, eventually leading to possible fibrosis and ulceration. April 6, The cells grew and spread with fervor. While I applaud the authors for being the first to study ketogenic diet in lymphedema, the study suffers from poor methodology which makes it difficult to rely on. Their conversation began an ongoing collaboration to address this question: Could the ketogenic diet work for women who are struggling with lipedema? Talk with your doctor and family members or friends about deciding to join a study. In this trial we will evaluate an entirely novel pro-lymphangiogenic strategy, not based on the delivery of lymphangiogenic growth factors, but rather based on modulating lymphatic endothelial cell metabolism. Pain reduction.