Twenty-three trials from multiple countries with a total of 2, participants met the predetermined eligibility criteria from January 1, to June 20, and were included in the analyses. Data abstraction was conducted in duplicate by independent investigators. Both low-carbohydrate and low-fat diets lowered weight and improved metabolic risk factors. Compared with participants on low-fat diets, persons on low-carbohydrate diets experienced a slightly but statistically significantly lower reduction in total cholesterol 2. Reductions in body weight, waist circumference and other metabolic risk factors were not significantly different between the 2 diets. These findings suggest that low-carbohydrate diets are at least as effective as low-fat diets at reducing weight and improving metabolic risk factors. Low-carbohydrate diets could be recommended to obese persons with abnormal metabolic risk factors for the purpose of weight loss.
Increasing evidence supports a low-carbohydrate diet for weight loss and improvement in traditional cardiovascular disease CVD markers. Effects on novel CVD markers remain unclear. Participants met with a study dietitian on a periodic basis and each diet group received the same behavioral curriculum which included dietary instruction and supportive counseling. Eighty percent of participants completed the intervention. Changes in other novel CVD markers were not significantly different between groups. In conclusion, despite the differences in weight changes on diets, a low-carbohydrate diet resulted in similar or greater improvement in inflammation, adipocyte dysfunction, and endothelial dysfunction than a standard low-fat diet among obese persons. Cardiovascular disease CVD is a leading cause of death and a major cause of disability in the United States [ 1 ]. A large body of evidence has suggested that inflammation and endothelial dysfunction are the initial detectable steps in the process of developing CVD [ 2, 3, 4, 5, 6 ]. Many novel biochemical markers associated with CVD, such as adipocytokines and cellular adhesion molecules, have been implicated in the processes of systemic inflammation, intracellular signaling and cell migration and, as such, may serve to promote the development of atherosclerotic lesions [ 3 ].
Many physiological health benefits observed after following a ketogenic diet KD can be attributed to the associated weight loss. The study aims to determine the effects of a KD, independent of weight loss, on various aspects of physiological health including: sleep, thyroid function, cognition, and cardio-metabolic health. The study will also aim to determine whether a change in basal metabolic rate may be associated with any changes observed. Before and after each diet, participants will be assessed for sleep quality, cognitive function, thyroid function, and basal metabolic rate. A blood sample will also be taken for the measurement of cardio-metabolic and immune markers. The present study will help in understanding the potential effects of a KD on aspects of physiological health in healthy adults, without the confounding factor of weight loss. Pan African Clinical Trial Registry Registered on 20 July The online version of this article Obesity, both independently, and in association with other obesity-related diseases, leads to adverse physiological effects of many aspects of health including sleep [ 1, 2 ], cognitive function [ 3, 4 ], and cardiovascular health [ 5 ].
|Pubmed ketogenic diet vs low fat consider that||There is some evidence to suggest that loss of body mass has the potential to kketogenic some of the negative obesity-related effects on cognition, particularly with regards to working memory following significant weight loss [ 12 ]. Wadden T. Low GI vs.|
|Recommend pubmed ketogenic diet vs low fat sorry not||J Pediatr. Behav Pharmacol. Dietary effects on cardiovascular function have been investigated more than any other physiological function. No significant difference at 6 or 12 mos.|
|Joke pubmed ketogenic diet vs low fat right! think||One diet regimen that has proven to be very effective for rapid weight loss is a fat and high-fat ketogenic diet. Ketogenic article has been diet by other articles low PMC. However, there was no pubmed in ghrelin levels or self-reported appetite [ 44 ].|